Nucleic Acid Databases

 

Nucleic acid databases play a crucial role in storing, organizing, and providing access to nucleotide sequences and related information. These databases are invaluable for bioinformatics, genetics, molecular biology, and various fields in zoology. Nucleotide data base include following databases

 1. GenBank

 GenBank is a comprehensive database of publicly available nucleotide sequences and their protein translations. It is maintained by the National Center for Biotechnology Information (NCBI), a division of the National Institutes of Health (NIH), USA.

 GenBank includes a wide variety of data such as DNA sequences, RNA sequences, and protein translations from numerous organisms, including animals, plants, bacteria, and viruses.

 Features of Genbank: 

 1)      Access to sequence data in several formats (FASTA, GenBank).

2)      Links to related data such as protein structures and published research.

3)      Provides a search interface for retrieving specific sequences.

We can explore genbank from GenBank Overview (nih.gov) 

2. DDBJ (DNA Data Bank of Japan)

 DDBJ is the DNA database managed by the National Institute of Genetics in Japan. It is part of the International Nucleotide Sequence Database Collaboration (INSDC), which also includes GenBank and EMBL.

 Like GenBank, DDBJ stores nucleotide sequences from a wide range of organisms. 

Features of DDBJ:

1.   Allows submission and retrieval of sequence data.
2.   Provides various tools for sequence analysis.
3.  Acts as a repository for genomic information related to various species, especially those of interest to Asian researchers.

We can explore DDBJ from https://www.ddbj.nig.ac.jp

 

3. EMBL (European Molecular Biology Laboratory) Database

   The EMBL nucleotide sequence database, now part of the European Nucleotide Archive (ENA), is a European repository for nucleotide sequences. It is hosted by the European Bioinformatics Institute (EBI).

 EMBL contains nucleotide sequence data from a wide array of species, including vertebrates, invertebrates, plants, and microorganisms.

 Features of EMBL:

1.     Data submission and retrieval services.
2.    Integration with other biological databases like UniProt for protein sequences and PDB for protein structures.
3.  Tools for sequence alignment, phylogenetic analysis, and genome annotation.

We can explore the EMBL from EMBL-EBI homepage | EMBL-EBI

   4. NDB (Nucleic Acid Database) 

The Nucleic Acid Database (NDB) focuses on three-dimensional structural information of nucleic acids such as DNA and RNA. It is maintained by Rutgers University in collaboration with the Research Collaboratory for Structural Bioinformatics (RCSB). 

 NDB includes structural data from X-ray crystallography and NMR spectroscopy on DNA and RNA molecules.

 Features of NDB:

1.     Provides access to 3D structures of nucleic acids.
2.     Links to related databases such as PDB for protein structures.
3.    Tools for visualizing and analyzing nucleic acid structures.

We can explore NDB from NAKB

 You Can also read Nucleic Acid Databases , Biological Databases , Primary, Secondary and Composite Databases, Nucleic Acid Databases